The Effects of CBD: Men vs. Women

The Effects of CBD: Men vs. Women

Men are from Mars, women are from Venus. Or so they say. While most research has focused on the therapeutic effects of CBD, one of the big questions yet to be fully answered is how certain cannabinoids affect men versus women. Let’s find out. 

Women and men are different in many ways. Body shapes and sizes vary and so do the way our bodies work. The endocannabinoid system (ECS) is a subject that is gaining momentum to help explain the biological effects of CBD and how it affects us differently. Every person has a unique endocannabinoid system that will determine how your body responds to CBD. The key to the ECS working properly is the healthy interaction of neurotransmitters, cannabinoids and hormones.

Why the ECS System Matters

The ECS is a natural system within each one of our bodies that helps regulate our sleep, mood, and appetite. It’s a complex network that regulates many of these bodily functions.

The Endocannabinoid System essentially helps maintain homeostasis which tries to keep your internal environment stable no matter what’s going on in the environment around you.

When something is operating outside of the optimal range, your body activates the ECS to help correct it. For example, when you’re really hot and begin to sweat, your ECS is working to cool you down. Hunger pangs? That’s your ECS helping remind you to eat because you need fuel in order to be energized. The ECS does this via cannabinoid receptors found in select tissues.

While there are many moving parts to the system, doctors and scientists have broken it down into 3 main parts:

  • Cannabinoid receptors: These receptors interact with both endocannabinoids and phytocannabinoids.
  • Endocannabinoids: These are the cannabinoids your body makes itself.
  • Enzymes: These are responsible for both creating and breaking down endocannabinoids.

A great way to think of these parts are keys and locks. The endocannabinoids act as the “keys” and receptors act as the “locks” in the system. By turning these keys, the system sends signals throughout your body and helps regulate many physiological functions. These functions include a multitude of things such as:

  • Pain perception
  • Learning and memory
  • Appetite
  • Mood

Once the endocannabinoids have done their job and brought balance, certain enzymes come along to break them down and prevent them from going too far and upsetting the balance in the opposite direction. Genius!

Here’s a look at some studies and research findings on how CBD affects men and women, as well as some potential health benefits of CBD.

Research on CBD & Women

Studies have shown that CBD can be used to help treat certain conditions unique to women, such as premenstrual syndrome, menopause and more. In 2019, out of the 64 million Americans who reported trying CBD, the majority of CBD users were female.


If you were to ask any woman about PMS, they’ll likely agree it can be one of the worst pains you can experience. Cramps, mood swings, nausea, anxiety, and bloating are just some of the many symptoms women experience during their menstrual cycles each month.

Studies show CBD is linked to alleviating the symptoms of premenstrual syndrome and menstruation.   This study explains how Estrogen easily breaks down and absorbs cannabinoids such as CBD, enhancing the effects of both. CBD then taps into the body’s endocannabinoid system to help regulate estrogen levels, which in turn can help tone down some of the unpleasant symptoms of PMS.

Sex Drive

A major complaint from menopausal women is a decreased libido. When menopause hits, estrogen levels drop, which can lead to decreased arousal and often times painful sex for women. Research has shown that CBD can give estrogen an extra boost in women experiencing these symptoms. However, it’s important to speak with your doctor before starting any new treatment to ensure safety and dosage.

CBD and Anxiety

According to the Anxiety and Depression Association of America, about 264 million people worldwide have an anxiety disorder. Women are nearly twice as likely as men to be diagnosed with an anxiety disorder in their lifetime. In the past year, the prevalence of any anxiety disorder was higher for females (23.4%) than for males (14.3%). 

Chances are, you probably know of someone who is dealing with an anxiety disorder. It has a tremendous impact on how you function affecting work, home life and relationships. Studies have demonstrated that CBD can reduce anxiety and stress, making it easier to manage in your day-to-day life.

Research on CBD & Men

CBD is commonly used for similar reasons among both men and women, but the experiences differ between genders. 

CBD provides men-specific benefits (see below); however, most men will probably require a higher dosage of CBD than women to achieve the beneficial effects. This is because on average, men weigh more than women. However, only a handful of medicines and supplements are dosed by weight. Women often end up receiving higher mg/kg drug doses than they should in light of specific weight differences, thus resulting in higher concentrations and higher exposure.

Since men produce more testosterone, this is what CBD interacts with. In fact, this study by the National Library of Medicine showed CBD can help boost testosterone and libido because it interacts with the cannabinoid receptors found in testicular tissue.

Some research has shown the initial increase in testosterone only lasts for a little while (*but not to such an extent as THC). Even though CBD may serve as an aphrodisiac for men, it doesn’t last that long. Also, the amount of time it lasts will vary from one person to another.

CBD & Blood Pressure

High blood pressure is a serious condition. According to the CDC, more men than women are affected by high blood pressure, which increases their risk for heart disease and stroke.

A recent study found that administering a single dose of CBD oil immediately before a stress test reduced the resting blood pressure of male participants. Research suggests that the antioxidant properties of CBD could help reduce inflammation, which decreases anxiety and stress that can lead to high blood pressure.

ED Issues

Approximately 52% of men between the ages of 40 and 70 have problems with sexual function. This figure is estimated to increase to 322 million globally by 2025. Erectile dysfunction (ED) is a common issue that men deal with that increases with age. 

Since CBD is known for its ability to reduce anxiety and stress, it could be effective as a short-term treatment for these issues in addition to anxiety. Another study found that CBD has antidepressant properties. Why does depression and stress matter? According to doctors, ED is caused by a range of physical and psychological factors such as depression, stress, heart diseases, diabetes, and high blood pressure.

(Disclaimer: Most of the information regarding CBD’s effectiveness in treating erectile dysfunction is based only on findings from these reports and studies. There is no direct proof that CBD can treat ED.)

Why lost range.®

Although some sex differences exist in how our bodies react to stressors, men and women can greatly benefit from adding CBD to their wellness routine.

At lost range.®, we make a commitment to our customers by delivering CBD that adheres to the highest possible standards of quality. Our mission is to help men and women find natural remedies that will drive them through their endeavors. We are proud of our products and strive for total transparency every step of the way.

If you would like to know more about our products and brand, our staff is always at your service for any questions. Contact us here today. 

To check out our full line of premium, hand-made, small-batch CBD products, click here!

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