CBG and Gut Health

CBG and Gut Health

The world of wellness continues to evolve, and cannabinoids are at the forefront of this health revolution. While most people are familiar with CBD (cannabidiol), there’s a lesser-known yet equally promising cannabinoid beginning to make waves: CBG, or cannabigerol. Known as the “mother cannabinoid,” CBG has been gaining attention for its impressive array of potential health benefits, including its positive effects on gut health.

At lost range.®, we’re passionate about natural, plant-powered wellness, which is why we’re excited to explore how CBG can support a healthy digestive system. In this blog, we’ll break down the science of CBG, its role in gut health, and how it works in tandem with CBD to help your body function at its best. 

What is CBG?

CBG, or cannabigerol, is one of more than 100 cannabinoids found in the cannabis plant. It’s often referred to as the “mother of all cannabinoids” because it’s the precursor from which other cannabinoids like CBD, THC, CBC, and others are synthesized. In the early stages of the cannabis plant’s life, CBG exists in its acidic form, CBGA (cannabigerolic acid), which then breaks down into other cannabinoids as the plant matures.

Because CBG is usually present in lower concentrations than CBD or THC (typically less than 1%), it has historically been harder and more expensive to extract. However, with increased interest and advanced cultivation techniques, specially bred hemp strains now offer higher levels of CBG, making it more accessible and affordable.

But what’s behind all the buzz? Let’s dive into why CBG is gaining popularity, especially when it comes to gut health.

The Endocannabinoid System and Gut Health

To understand how CBG supports gut health, it’s important to first understand the endocannabinoid system (ECS)—a complex cell-signaling network in the human body. The ECS helps regulate a wide array of essential functions, including:

  • Appetite and digestion
  • Immune response
  • Inflammation
  • Pain sensation
  • Mood and stress levels

The ECS is composed of endocannabinoids (produced naturally by the body), receptors (CB1 and CB2), and enzymes that break down cannabinoids after they've fulfilled their role. These receptors are found throughout the body, including in the gastrointestinal (GI) tract.

Research suggests that the ECS plays a vital role in maintaining gut homeostasis, which refers to the balance and health of your digestive system. This includes processes like nutrient absorption, intestinal permeability, and the regulation of gut inflammation. When the ECS is functioning properly, it helps keep your gut running smoothly. When it’s out of balance, issues like inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), leaky gut, and gut dysbiosis (an imbalance in gut bacteria) can arise.

CBG and Gut Health

1. Anti-Inflammatory Effects

CBG has shown promise as a potent anti-inflammatory agent. In preclinical studies, CBG has been shown to reduce inflammation in the intestines. One study published in Biochemical Pharmacology found that CBG helped reduce symptoms of colitis, an inflammatory bowel condition, in mice. Researchers noted that CBG reduced inflammatory markers and improved overall gut function.

For those suffering from conditions like IBD or Crohn’s disease, which are often marked by chronic inflammation, CBG’s ability to help reduce that inflammation could potentially provide much-needed relief.

2. Antibacterial and Antimicrobial Properties

CBG has shown antibacterial properties, including the ability to fight antibiotic-resistant bacteria like MRSA. A healthy gut is dependent on a balanced microbiome—CBG’s ability to target harmful bacteria without damaging beneficial microbes could be a powerful tool in maintaining gut harmony.

By supporting a healthy microbial balance, CBG could help reduce the risk of gut dysbiosis, which has been linked to a wide range of issues from bloating and constipation to mood disorders and weakened immunity.

3. Neuroprotective Effects on the Gut-Brain Axis

The gut is often referred to as the “second brain” due to its close relationship with the central nervous system. This is known as the gut-brain axis, a bidirectional communication network between your GI tract and your brain. Disruptions in the gut-brain axis are believed to contribute to anxiety, depression, and other mood disorders, often in tandem with digestive issues.

CBG interacts with the ECS in ways that may help calm both the gut and the mind, promoting balance in the gut-brain connection. For people dealing with stress-related digestive issues like IBS, this may be especially important.

4. Appetite Regulation and Digestive Support

CBG has also been found to stimulate appetite in animal studies. Unlike THC, which can lead to excessive hunger (aka the “munchies”), CBG appears to support appetite without the psychoactive effects. This could be beneficial for individuals with chronic illness, eating disorders, or other conditions where appetite and digestion are affected.

CBG may also help relax smooth muscle tissue, which lines the digestive tract. This could support smoother digestion and reduce cramping or spasms that are common in GI disorders.

CBG vs. CBD: What’s the Difference?

While CBD and CBG both interact with the ECS, they do so in different ways. CBD is known for its calming, anti-anxiety effects and its ability to reduce inflammation. CBG, on the other hand, binds more directly with CB1 and CB2 receptors, which could make it more effective in some areas, particularly when targeting inflammation and bacterial overgrowth in the gut.

But here’s the magic: when used together, CBD and CBG can create a synergistic effect, enhancing the therapeutic potential of both compounds. This is known as the entourage effect, where multiple cannabinoids work together to provide better outcomes than any single compound alone.

That’s why we created our CBD+CBG Gummies, which harness the power of both cannabinoids in one tasty, convenient package.

lost range.® CBD+CBG Gummies

At lost range.®, we’re committed to crafting premium, small-batch products that help support your health from the inside out. That’s why we’re proud to offer our CBD+CBG Gummies, designed to help you feel your best, especially when it comes to gut health, focus, and calm.

Why Choose lost range.® CBD+CBG Gummies?

  • Full-Spectrum Cannabinoids: Each gummy contains a balanced ratio of CBD and CBG, delivering the entourage effect for maximum benefit.
  • Naturally Derived: We source our hemp from trusted farms in Colorado, ensuring it's grown without pesticides or harmful chemicals.
  • High Bioavailability: Our gummies are crafted for optimal absorption, allowing your body to make the most of every milligram.
  • Delicious and Convenient: Available in sour blue raspberry, the flavor makes these an easy addition to your daily wellness routine.
  • Third-Party Lab Tested: All our products undergo rigorous testing to ensure purity, potency, and consistency.

Shop yours now at lostrangecbd.com.

Other Natural Gut-Boosting Compounds That Pair Well With CBG

To supercharge your gut health routine, CBG can be paired with other natural compounds like:

  • Probiotics and prebiotics: support a healthy gut microbiome.
  • Turmeric: a natural anti-inflammatory that complements CBG’s effects.
  • Ginger: aids digestion and relieves nausea.
  • Peppermint oil: helps relax the GI tract.
  • Fiber-rich foods: promote bowel regularity and microbiome balance.

Incorporating these into your wellness routine alongside a quality CBD+CBG supplement may help improve digestive health over time.

Final Thoughts: Nurture Your Gut with the Power of CBG

Your gut does more than just digest food—it influences your mood, your immune system, and your overall well-being. With growing scientific interest in the benefits of cannabinoids like CBG, it’s becoming clear that these plant compounds hold significant promise in supporting digestive health.

Whether you’re managing a specific condition like IBS or simply looking to optimize your wellness, incorporating CBG into your routine may offer the natural support your gut needs to thrive.

At lost range.®, we believe in the power of nature and the science of cannabinoids. Our CBD+CBG Gummies are a delicious way to tap into that power, one bite at a time.

Ready to support your gut the natural way?
Shop lost range.® CBD+CBG Gummies today and feel the difference that full-spectrum wellness can make.


Frequently Asked Questions (FAQs)

1. Is CBG safe to take every day?

Yes, current research and anecdotal evidence suggest that CBG is generally well-tolerated when used consistently and responsibly. As with any supplement, it’s best to start with a low dose and increase gradually based on how your body responds. We recommend consulting with a healthcare provider, especially if you're taking medications or managing a chronic health condition.

2. How long does it take to notice the effects of CBG on gut health?

The timeline varies from person to person. Some individuals report improvements in digestion or bloating within a few days, while others may need several weeks of consistent use to notice changes. Because gut health is deeply connected to diet, lifestyle, and microbiome balance, CBG works best as part of a long-term wellness plan rather than a quick fix.

3. Can I take CBG if I’m already on probiotics or digestive enzymes?

Yes! CBG can complement digestive supplements like probiotics and enzymes without interfering. In fact, using CBG alongside gut-supporting supplements may provide a more holistic approach to digestive health. Just be sure to space out dosages and monitor how your body responds.

4. Are there any side effects of CBG I should be aware of?

While CBG is considered safe, some people may experience mild side effects such as dry mouth, drowsiness, or changes in appetite, especially when taking higher doses. These effects are generally temporary and can often be mitigated by adjusting dosage or frequency.

5. Will CBG show up on a drug test?

CBG itself is non-psychoactive and not typically screened for in drug tests. However, lost range.® CBD+CBG Gummies contain full-spectrum hemp extract, which includes trace amounts of THC (<0.3%). While unlikely, this may result in a false-positive on certain drug screenings. If drug testing is a concern, consider speaking with your employer or opting for THC-free products.


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